7/5/2023 0 Comments Sequence alignment 4peaks![]() Sequence alignment is a technique for identifying regions of sequence similarity by arranging genome sequences to obtain the function, structure, or evolutionary relationship between the sequences to be aligned. It is the key link to apply high-performance computing to biology. ![]() ![]() In the research of bioinformatics ( Wang et al., 2015), biological sequence alignment is one of the important processes of similarity analysis between unknown and known molecular sequences, the basis of biological sequence analysis and database search, and used in the sequence assembly. A star alignment algorithm is designed and generated to demonstrate the development process.Īlignment is a common and important approach in biology study. Based on our constructed pairwise sequence alignment algorithm component library and the convenient software platform PAR, a few expansion domain components are developed for multiple sequence alignment application domain, and specific multiple sequence alignment algorithm can be designed, and its corresponding program, i.e., C++/Java/Python program, can be generated efficiently and thus enables the improvement of the development efficiency of complex algorithms, as well as accuracy of sequence alignment calculation. Multiple sequence alignment algorithms are more complex, redundant, and difficult to understand, and it is not easy for users to select the appropriate algorithm some computing errors may occur. Existing research focuses mainly on the specific steps of the algorithm or is for specific problems, lack of high-level abstract domain algorithm framework. 3School of Computer and Information Engineering, Jiangxi Normal University, Nanchang, ChinaĪs a key algorithm in bioinformatics, sequence alignment algorithm is widely used in sequence similarity analysis and genome sequence database search.2School of Software, Jiangxi Normal University, Nanchang, China. ![]()
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